A Prescription Digital Therapeutic to Support Unsupervised Buprenorphine Initiation for Patients With Opioid Use Disorder: Protocol for a Proof-of-Concept Study.

Background: Home-based (unsupervised) buprenorphine initiation is considered safe and effective, yet many patients report barriers to successful treatment initiation. Prescription digital therapeutics (PDTs) are software-based disease treatments regulated by the US Food and Drug Administration (FDA). The reSET-O PDT was authorized by the FDA in 2018 and delivers behavioral treatment for individuals receiving buprenorphine for opioid use disorder (OUD).

Modeling and characterization of a few-mode EDFA supporting four mode groups for mode division multiplexing.

Numerical and experimental study of a Few-Mode (FM) Erbium Doped Fiber Amplifier (EDFA) suitable for mode division multiplexing (MDM) is reported. Based on numerical simulations, a Few-Mode Erbium Doped Fiber (FM-EDF) has been designed to amplify four mode groups and to equally amplify LP11 and LP21 mode groups with gains greater than 20 dB and with a differential modal gain of less than 1 dB. Experimental results confirmed the simulations with a good concordance.

Two mode transmission at 2×100 Gb/s, over 40 km-long prototype few-mode fiber, using LCOS-based programmable mode multiplexer and demultiplexer.

We present a novel optical transmission system to experimentally demonstrate the possibility of mode division multiplexing. Its key components are mode multiplexer and demultiplexer based on a programmable liquid crystal on silicon panel, a prototype few-mode fiber, and a 4×4 multiple input multiple output algorithm processing the information of two polarization diversity coherent receivers. Using this system, we transmit two 100 Gb/s PDM-QPSK data streams modulated on two different modes of the prototype few-mode fiber.

PDM-QPSK: on the system benefits arising from temporally interleaving polarization tributaries at 100Gb/s.

We experimentally study, over a dispersion-managed link relying on low chromatic dispersion fibre, the origins of the system benefits provided by temporally interleaving the polarization tributaries of 100Gb/s coherent RZ-PDM-QPSK by half a symbol period. Hence, we demonstrate that the amount of benefits provided by this technique is dependent on the configuration of the WDM transmission system.

[Orbito-palpebral prosthesis retained by intraosseous implants].

The use of intraosseous implants, whose tolerance is continually improving, constitutes an important progress in the field of prosthetic rehabilitation. In particular, titanium implants largely resolve the problem of retention of craniofacial prostheses. Our experience, based on that of Swedish authors concerning the extra-oral use of intraosseous implants, was sufficiently convincing to adopt this effective technique in our patients candidates for prosthetic rehabilitation.