The potentiation of pharmacological effects can be achieved through several strategies, such as the association of substances and delivery in nanostructured systems. In practice, potentiation can be measured by the law of mass action and joint evaluation of the combination index (CI) and dose-response curves. In this context, this study aimed to evaluate the anti-inflammatory effect of the association of β-caryophyllene and indomethacin in the free form and delivered in nanoemulsions using the in vitro model of LPS-stimulated murine macrophage.
View Article and Find Full Text PDFPurpose: To quantify the number of SARS-CoV-2 infections in students and teachers in 14 Secondary schools in eastern Saxony, Germany. Seroprevalence of SARS-CoV-2 antibodies in study population. Number of undetected cases.
View Article and Find Full Text PDFObjective: To quantify the number of undetected SARS-CoV-2 infections in educational settings.
Design: Serial SARS-CoV-2 seroprevalence study before and during the second wave of the COVID-19 pandemic.
Setting: Secondary school in Dresden, Germany.
Objective: To quantify the number of SARS-CoV-2 infections in secondary schools after their reopening in May 2020.
Design: Repeated SARS-CoV-2 seroprevalence study after the reopening of schools and 4 months later.
Setting: Secondary school in Dresden, Germany.