The effect of naloxone and the kappa antagonist MR 1452 MS on myocardial infarction in rats.

The intravenous infusion of naloxone (Nal) (0.17 mg/kg/min) and of the selective kappa antagonist MR 1452 MS (0.07 mg/kg/min) on rats with left coronary artery occlusion was studied.

Humoral factors involved in the regulation of sodium-fluid balance in man. III. Renal prostaglandins and renin-angiotensin-aldosterone system in hypertensive disorders.

An estimation of renal secretion rates of PGE2 and PGF2 alpha, in parallel with renin-angiotensin-aldosterone system and catecholamines was performed on control subjects, essential hypertensive, and renovascular hypertensive patients. In essential hypertensive patients with normal plasma renin activity (PRA) and normal catecholamines level. We did not find any changes in the renal prostaglandin (PG) secretion rate as compared to the control subjects.

[Levels of immunoreactive insulin in laser irradiated rats].

The authors described the results from a study on immonoreactive insuline in rats after their irradiation in the region of the pancreas with rubine laser with beam energy of 0, 13 Joul/impulse. The irradiation was made singly with 7--10 impulses. The level of immunoreactive insulin was raised to 33,83 microliter I/ml in nonirradiated rats and to 48 microliter/ml per 24 hours after irradiation and reached its maximum of 54 microliter/ml after 48 hours of its irradiation, but then returned to its normal values after 72 hours.