Safety and efficacy findings from a non-interventional study of a new hyaluronic acid/sorbitol formulation (GO-ON® matrix) for intra-articular injection to relieve pain and disability in osteoarthritis patients.

This non-interventional study was intended to examine the efficacy and tolerability of intra-articular injections with the GO-ON® matrix, a new viscosupplement product made of non-animal sodium hyaluronate combined with the oxygen free radical scavenger sorbitol, when used in routine clinical practice. A total of 1 147 patients (43.5% male, 53,5% female, 3% missing) aged on average 63.

Vitamin D-insufficiency: An estimate of the situation in Germany.

Background: Vitamin D insufficiency is increasingly recognized as an important risk factor in the pathogenesis of falls and fractures and may increase the risk of other diseases. The aim of this study was to obtain information about the vitamin D supply from a representative cohort of the German population.  

Methods: 264 General practitioners participated in the DeViD-Trial (D-Vitamin in Deutschland) by taking blood samples from their consenting daily ambulant patients regardless of the actual reason for consultation.

[Treatment of osteoarthritis with cristalline glucosamine sulfate. Results of the IDEAL-study].

Aims And Methods: The treament of patients with mild to moderate osteoarthritis of the knee with cristalline glucosamine sulfate (CGS; dona) under real life conditions was documented for 6 months in a multicenter, prospective, non-controlled, noninterventional trial. In addition to efficacy evaluated with Lequesne's index, changes in use of analgesics and the incidence of related adverse events were to be assessed during the intake CGS. Furthermore, quality of life was to be documented using a patient-diary.

[Vitamin D deficiency in Germany, is it a danger for increased morbidityand mortality?].

Vitamin D regulates the calcium-phosphate metabolism and thereby plays an important role for the integrity and functioning of bone, muscle and nerves. Studies have shown furthermore an influence on certain types of cancer, diabetes and cardiovascular diseases. Vitamin D is mainly produced by the skin.