Publications by authors named "C Kenneth Dodd"

Background/objectives: For low- and middle- income country (LMIC) settings, a global nutrition transition is rapidly emerging as diets shift, resulting in a dual burden of malnutrition. High quality dietary intake data for these populations is essential to understand dietary patterns contributing to these nutrition issues. New technology is emerging to address dietary assessment challenges; however, it is unknown how researchers conducting studies with LMIC populations or under-served groups in high-income countries adopt technology-assisted methods.

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Purpose: To describe the development of INSIGHT, a real-world data quality tool to assess completeness, consistency, and fitness-for-purpose of observational health data sources.

Methods: We designed a three-level pipeline with data quality assessments (DQAs) to be performed in ConcePTION Common Data Model (CDM) instances. The pipeline has been coded using R.

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Article Synopsis
  • The study compares the accuracy of experienced surgeons and a machine learning model (ResNet50v2) in predicting patient outcomes from knee replacement radiographs.
  • The model performed better than the surgeons, identifying 71% of patients with poor outcomes and 82% with excellent outcomes, while the surgeons struggled significantly.
  • The findings suggest that there are specific radiographical features linked to poor outcomes that surgeons may not recognize, indicating a need for further research to improve surgical techniques and patient results.
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Article Synopsis
  • Preeclampsia (PE) is linked to hypertension and immune responses during pregnancy, with COVID-19 history potentially increasing PE-like symptoms and cognitive issues in affected individuals.
  • * Researchers isolated CD4+ T cells from women with PE and those without (some with COVID-19 history) and injected them into pregnant rats to study their impact on blood pressure and cognitive function.
  • * The study found that PE, particularly with a COVID-19 history, caused higher blood pressure and cognitive dysfunction in recipient rats, suggesting a significant role of CD4+ T cells in these pregnancy complications.
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