Publications by authors named "C Kelgeri"
Hepatitis B elimination objectives can only be realised if new patient linkage to care is matched by long-term patient retention in care. We previously showed in adult chronic hepatitis B (CHB) patients that retention in care was inferior in younger patients and in patients from non-Asian ethnicities. The present study explores further the rates and determinants of loss to follow-up in a cohort of 271 young patients (aged 16-21 years at baseline).
View Article and Find Full Text PDFHepatitis B e antigen (HBeAg) loss is a key event in the natural history of chronic hepatitis B virus infection. The rate and determinants of HBeAg loss depend upon cohort characteristics at baseline. Few studies have examined the age-dependent rate, and none have examined the effect of patient sex and ethnicity on the age-dependant rate.
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- Liver transplantation (LT) for children with glycogen storage disease type 1b can reduce infection-related hospital visits but does not improve neutropenia or the need for granulocyte colony-stimulating factor (G-CSF) post-transplant.
- In a study of eight children, most showed signs of graft rejection despite adequate immunosuppression, and while body mass index (BMI) significantly decreased, height remained unchanged after LT.
- The use of dapagliflozin helped stop G-CSF administration and led to lower gastrointestinal and infection-related issues, but did not enhance neutrophil counts.
Objective: To evaluate trends in etiology and outcomes of neonatal liver failure (NLF) over 30 years retrospectively at a single institution.
Study Design: Inclusion criteria for this retrospective cohort study were babies presenting at a chronological age of ≤28 days between 1991 and 2020 with prothrombin time ≥20 seconds and biochemical liver injury. Demographics, etiology, laboratory investigations, need for extrahepatic organ support, acute kidney injury, and intervention with liver transplant (LT) were recorded.