Publications by authors named "C Katsanos"

Article Synopsis
  • Recent research suggests a link between diabetes-related lower-extremity complications (DRLECs) and cognitive changes, but findings are inconsistent and no systematic reviews have previously been conducted on this topic.* -
  • A systematic review analyzed 13 studies comparing cognitive performance in individuals with diabetes, both with and without DRLECs; results showed mixed outcomes with some studies indicating significant differences while others found none.* -
  • Overall, while there may be a relationship between DRLECs and cognition in diabetes, the lack of consistent methodologies across studies makes it difficult to draw clear conclusions.*
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Context: Humans with obesity and insulin resistance exhibit lipid accumulation in skeletal muscle, but the underlying biological mechanisms responsible for the accumulation of lipid in the muscle of these individuals remain unknown.

Objective: We investigated how plasma insulin modulates the extraction of circulating triglycerides (TGs) and non-esterified fatty acids (NEFAs) from ingested and endogenous origin in the muscle of lean, insulin-sensitive humans (Lean-IS) and contrasted these responses to those in humans with obesity and insulin resistance (Obese-IR).

Methods: The studies were performed in a postprandial state associated with steady-state plasma TG concentrations.

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Purpose Of Review: This review aims to critically examine how VLCKD affects plasma lipoprotein, lipid and cholesterol metabolism. Cardiovascular disease is a worldwide health problem affecting millions of people and leading to high rates of mortality and morbidity. There is a well-established association between cardiovascular disease and circulating cholesterol.

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Context: Humans with obesity and insulin resistance exhibit lipid accumulation in skeletal muscle, but the underlying biological mechanisms responsible for the accumulation of lipid in the muscle of these individuals remain unknown.

Objective: We investigated how plasma insulin modulates the extraction of circulating triglycerides (TGs) and non-esterified fatty acids (NEFAs) from ingested and endogenous origin in the muscle of lean, insulin-sensitive humans (Lean-IS) and contrasted these responses to those in humans with obesity and insulin resistance (Obese-IR).

Methods: The studies were performed in a postprandial state associated with steady-state plasma TG concentrations.

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Purpose Of Review: This review aims to explore in-depth the different aspects of the association between very low-calorie ketogenic diet (VLCKD), obesity and obesity-related thyroid dysfunction.

Recent Findings: The VLCKD, proposed as a non-pharmacological strategy for the management of certain chronic diseases, is becoming increasingly popular worldwide. Initially used to treat epilepsy, it has been shown to be effective in controlling body weight gain and addressing various pathophysiological conditions.

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