Publications by authors named "C Karuthan"

Background: Patients scheduled for coronary artery bypass graft (CABG) surgery tend to have persistent symptoms of anxiety and depression. Course of hospital stay post-CABG procedure has become increasingly shorter over the last few decades. This pilot study was conducted to develop and test feasibility of MyEducation: CABG application as a learning tool to reduce anxiety and depression levels among patients undergoing CABG Surgery.

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Article Synopsis
  • The study investigates the differences in the oral microbiome among three groups: healthy individuals, those with oral potentially malignant disorders (OPMD), and oral cancer patients, using 16S rDNA sequencing.
  • The researchers identified a core oral microbiome predominantly comprised of the phyla Firmicutes and the genus Streptococcus, while also discovering unique microbiome profiles for each group.
  • Statistical analysis found significant differences in the oral microbiota between healthy individuals and cancer patients, suggesting that oral microbes could serve as potential biomarkers for distinguishing these conditions.
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Introduction: Gestational diabetes mellitus (GDM) increases risks for type 2 diabetes and cardiovascular diseases. Low glycaemic index (GI) diets improve cardio-metabolic outcomes in insulin-resistant individuals. We examined the feasibility of lowering GI through GI-based-education among Asian post-GDM women.

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Background And Purpose: Previous cell-based and animal studies showed mixed tocotrienols are neuroprotective, but the effect is yet to be proven in humans. Thus, the present study aimed to evaluate the protective activity of mixed tocotrienols in humans with white matter lesions (WMLs). WMLs are regarded as manifestations of cerebral small vessel disease, reflecting varying degrees of neurodegeneration and tissue damage with potential as a surrogate end point in clinical trials.

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