Publications by authors named "C Kanipe"

Bovine tuberculosis is mainly caused by Mycobacterium bovis. Bacillus Calmette-Guérin (BCG) is an attenuated strain of M. bovis which provides variable disease protection.

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Background: Mycobacterium bovis BCG is the human tuberculosis vaccine and is the oldest vaccine still in use today with over 4 billion people vaccinated since 1921. The BCG vaccine has also been investigated experimentally in cattle and wildlife by various routes including oral and parenteral. Thus far, oral vaccination studies of cattle have involved liquid BCG or liquid BCG incorporated into a lipid matrix.

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Background: Sexual harassment (SH) and sexual assault (SA) are serious public health problems among US service members. Few SH and SA prevention interventions have been developed exclusively for the military. Code of Respect (X-CoRe) is an innovative web-based, multilevel, SA and SH intervention designed exclusively for the active-duty Air Force.

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Article Synopsis
  • The study investigates the antiviral effects of recombinant bovine interferon lambda 3 (bovIFN-λ3) against bovine viral diarrhea virus (BVDV) specifically in bovine respiratory tract epithelial cells, which are key targets for BVDV infection.
  • Results show that while bovIFN-λ3 is effective in Madin-Darby bovine kidney cells (MDBK), it does not clear BVDV in bovine turbinate-derived primary epithelial cells (BTu) unless BTu cells are supplemented with the IL-28Rα subunit.
  • The findings indicate that both the quality and quantity of the IL-28Rα receptor subunit influence the sensitivity of cells to bovIFN
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Bovine tuberculosis is caused by , a member of the complex of mycobacterial species that cause tuberculosis in humans and animals. Diagnosis of bovine tuberculosis has relied on examinations of cell-mediated immune responses to proteins using tuberculin skin testing and/or interferon gamma release assays. Even when using these methods, disease detection during the earliest phases of infection has been difficult, allowing a window for cattle-to-cattle transmission to occur within a herd.

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