Publications by authors named "C K Uricchio"

Article Synopsis
  • The study evaluates a new glycemic pellets challenge (GPC) for testing insulin dysregulation in horses, comparing it with the traditional low-dose oral sugar test (OST).
  • In a randomized crossover trial with 24 adult horses, blood samples were taken at different time intervals after administering GPC and OST to measure blood glucose and insulin levels.
  • Results indicated that GPC was well-tolerated, led to higher glucose and insulin concentrations than OST, and highlighted the need to determine the best sample collection timing for accurate insulin measurement.
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Background: Diagnosis of pituitary pars intermedia dysfunction (PPID) using the thyrotropin-releasing hormone (TRH) stimulation test requires blood collection 10 minutes after TRH injection; it is unknown if small differences in timing affect test results.

Objective: To determine whether early or late sampling results in a significant (≥10%) difference in plasma adrenocorticotropic hormone (ACTH) concentration compared to standard 10-minute sampling.

Animals: Twenty-four healthy adult horses with unknown PPID status.

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The present study evaluated a novel intrauterine device for its effect on estrus suppression. The self-assembling intrauterine device (Upod) consists of three 12 mm × 26 mm elliptically shaped units each with a magnetic core and coated with a polymer (total weight 22.5 g).

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Background: Octreotide is a somatostatin analog that suppresses insulin secretion.

Hypothesis: We hypothesized that octreotide would suppress insulin concentrations in horses and that normal (N) horses and those with insulin dysregulation (ID) would differ significantly in their plasma glucose and insulin responses to administration of octreotide.

Animals: Twelve horses, N = 5, ID = 7.

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Reasons For Performing Study: Corneal thickness measurements of the equine globe using spectral-domain optical coherence tomography (SD-OCT) have not been reported.

Objectives: To determine corneal thickness measurements and the intra- and interoperator reliability of a portable SD-OCT device in equine eyes.

Study Design: Prospective observational study.

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