Image-guided Needle-Based Confocal Laser Endomicroscopy in the Prostate: Safety and Feasibility Study in 2 Patients.

To assess the safety and technical feasibility of needle-based forward-looking confocal laser endomicroscopy in prostate tissue. For this feasibility study, 2 patients with a suspicion of prostate cancer underwent transperineal needle-based confocal laser endomicroscopy during ultrasound-guided transperineal template mapping biopsies. After intravenous administration of fluorescein, needle-based confocal laser endomicroscopy imaging was performed with a forward-looking probe (outer diameter 0.

A Low-Cost Digital Colorimetry Setup to Investigate the Relationship between Water Color and Its Chemical Composition.

Developments in digital image acquisition technologies and citizen science lead to more water color observations and broader public participation in environmental monitoring. However, the implications of the use of these simple water color indices for water quality assessment have not yet been fully evaluated. In this paper, we build a low-cost digital camera colorimetry setup to investigate quantitative relationships between water color indices and concentrations of optically active constituents (OACs).

Exploring the Environmental Exposure to Methoxychlor, α-HCH and Endosulfan-sulfate Residues in Lake Naivasha (Kenya) Using a Multimedia Fate Modeling Approach.

Distribution of pesticide residues in the environment and their transport to surface water bodies is one of the most important environmental challenges. Fate of pesticides in the complex environments, especially in aquatic phases such as lakes and rivers, is governed by the main properties of the contaminants and the environmental properties. In this study, a multimedia mass modeling approach using the Quantitative Water Air Sediment Interaction (QWASI) model was applied to explore the fate of organochlorine pesticide residues of methoxychlor, α-HCH and endosulfan-sulfate in the lake Naivasha (Kenya).

Detection of clinically significant prostate cancer in biopsy-naïve men: direct comparison of systematic biopsy, multiparametric MRI- and contrast-ultrasound-dispersion imaging-targeted biopsy.

Objectives: To compare and evaluate a multiparametric magnetic resonance imaging (mpMRI)-targeted biopsy (TBx) strategy, contrast-ultrasound-dispersion imaging (CUDI)-TBx strategy and systematic biopsy (SBx) strategy for the detection of clinically significant prostate cancer (csPCa) in biopsy-naïve men.

Patients And Methods: A prospective, single-centre paired diagnostic study included 150 biopsy-naïve men, from November 2015 to November 2018. All men underwent pre-biopsy mpMRI and CUDI followed by a 12-core SBx taken by an operator blinded from the imaging results.

Synthetic Elastography Using B-Mode Ultrasound Through a Deep Fully Convolutional Neural Network.

Shear-wave elastography (SWE) permits local estimation of tissue elasticity, an important imaging marker in biomedicine. This recently developed, advanced technique assesses the speed of a laterally traveling shear wave after an acoustic radiation force "push" to estimate local Young's moduli in an operator-independent fashion. In this work, we show how synthetic SWE (sSWE) images can be generated based on conventional B-mode imaging through deep learning.