Establishment of iPSC-Derived MSCs Expressing hsa-miR-4662a-5p for Enhanced Immune Modulation in Graft-Versus-Host Disease (GVHD).

The immune-modulatory effects of mesenchymal stromal cells (MSCs) are widely used to treat inflammatory disorders, with indoleamine 2,4-dioxygenase-1 (IDO-1) playing a pivotal role in suppressing stimulated T-cell proliferation. Taking that three-dimensional (3D) cultures enhance MSCs' anti-inflammatory properties compared with two-dimensional (2D) cultures, the differentially expressed miRNAs were examined. Thus, we identified hsa-miR-4662a-5p (miR-4662a) as a key inducer of IDO-1 via its suppression of bridging integrator-1 (BIN-1), a negative regulator of the IDO-1 gene.

HfO-based ferroelectric synaptic devices: challenges and engineering solutions.

HfO-based ferroelectric memories have garnered significant attention for their potential to serve as artificial synaptic devices owing to their scalability and CMOS compatibility. This review examines the key material properties and challenges associated with HfO-based ferroelectric artificial synaptic devices as well as the recent advancements in engineering strategies to improve their synaptic performance. The fundamental physics and material properties of HfO-based ferroelectrics are reviewed to understand the theoretical origin of the aforementioned technical issues in ferroelectric HfO-based synaptic devices.

High- organic-inorganic hybrid dielectric material for flexible thin-film transistors and printed logic circuits.

A new photopolymerizable organic-inorganic (O-I) hybrid sol-gel material, AUP@SiO-184, has been synthesized and utilized as a gate dielectric in flexible organic thin-film transistors (OTFTs). The previously reported three-arm alkoxy-functionalized silane amphiphilic polymer has yielded stable O-I hybrid materials comprising uniformly dispersed nanoparticles in the sol state. In this study, a photosensitizer was introduced, facilitating curing effects under ultraviolet light.

Assessing the impact of marine litter hotspot on atmospheric microplastics: A study of a coastal village.

Marine litter and microplastics (MPs) represent pressing environmental challenges. However, the impact of marine litter on airborne MPs near marine litter hotspot remains unexplored. In this study, we simultaneously collected airborne MPs, weather factors, and air pollutants in a village near a marine litter hotspot across different seasons in Taiwan.

NIR-Reflective Black Photonic Films Designed for Effective LiDAR Recognition.

Conventional dark-tone paints absorb both visible light and near-infrared (NIR) wavelengths, posing a challenge for light detection and ranging (LiDAR) recognition in autonomous driving. To overcome this issue, various chemical and structural coating materials have been explored to selectively reflect NIR. In this study, we newly propose colloidal photonic crystals with a stopband in the NIR range, fabricated through the spontaneous formation of crystalline arrays of silica particles dispersed in a photocurable resin, as a potential solution.