Influential Factors on Survival in Laryngeal Cancer and Treatment Modalities Comparison.

Introduction Laryngeal cancer (LC) is the most common malignancy in otolaryngology, comprising 30-40% of head and neck malignancies. With an increasing incidence worldwide over the past few decades, LC has resulted in substantial strain on the NHS. There have been notable advancements in the treatment of LC over the years, particularly with the adoption of non-surgical methods, which emerged after the 1991 study conducted by the Veterans Affairs.

Bidirectional links between sleep and pain among heavy-drinking veterans with insomnia.

Study Objectives: Military veterans often suffer from chronic pain and sleep issues at a greater frequency than the general population, leading some to self-medicate with alcohol. While research shows a connection between sleep and pain, few studies have examined bidirectional links between sleep and pain at the daily level-or the extent to which alcohol use may moderate these associations.

Methods: Heavy-drinking veterans seeking treatment for insomnia ( = 109, 82.

Prognosis of Equivocal Interstitial Lung Abnormalities in a Health Check-up Population.

Rationale: Equivocal interstitial lung abnormality (ILA) involves less than 5% of any lung zone or presents unilaterally without satisfying the diagnostic criteria for ILA; however, the prevalence and prognosis of equivocal ILA are unknown.

Objectives: To investigate the prevalence and long-term prognosis of equivocal ILA.

Methods: This retrospective cohort study included individuals who underwent chest CT as part of a health check-up program in 2010 at St.

To Determine the Risk-Based Screening Interval for Diabetic Retinopathy: Development and Validation of Risk Algorithm from a Retrospective Cohort Study.

Background: The optimal screening interval for diabetic retinopathy (DR) remains controversial. This study aimed to develop a risk algorithm to predict the individual risk of referable sight-threatening diabetic retinopathy (STDR) in a mainly Chinese population and to provide evidence for risk-based screening intervals.

Methods: The retrospective cohort data from 117,418 subjects who received systematic DR screening in Hong Kong between 2010 and 2016 were included to develop and validate the risk algorithm using a parametric survival model.

Fossil amphibian offers insights into the interplay between monsoons and amphibian evolution in palaeoequatorial Late Triassic systems.

The severe greenhouse climate and seasonality of the early to mid-Late Triassic are thought to have limited terrestrial diversity at lower latitudes, but direct adaptations to these harsh conditions remain limited in vertebrates at the palaeoequator. Here, we present gen. et sp.