Publications by authors named "C K Dixit"

Background: Various clinical studies performed in adults have shown the relationship between craniofacial morphology and masticatory muscle function. However, the growth of the masticatory muscle has not received such attention, when compared with the volume of studies on the skeletal growth of face. With this background and considering the widespread use of ultrasonography (USG), the following study was undertaken to provide some insights into the relationship between muscle and bone and facial morphology.

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Due to their high sensitivity and selectivity, low cost, and good compatibility for sensor array integration, colorimetric gas sensors are widely used in hazardous gas detection, food freshness assessment, and gaseous biomarker identification. However, colorimetric gas sensors are usually designed for one-time discrete measurement because the sensing materials are entirely exposed to analytes during the sensing process. The fast consumption of sensing materials limits colorimetric sensors' applications in continuous analytes monitoring, increases the operation complexity and brings challenges for calibration.

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Although deep learning approaches are able to generate generic image features from massive labeled data, discriminative handcrafted features still have advantages in providing explicit domain knowledge and reflecting intuitive visual understanding. Much of the existing research focuses on integrating both handcrafted features and deep networks to leverage the benefits. However, the issues of parameter quality have not been effectively solved in existing applications of handcrafted features in deep networks.

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There is a plethora of chromatographic supports available in different shapes, sizes, functionalities, and chemical compositions, that could be employed for the numerous applications such as purification, scavenging, and target quantification. Therefore, it becomes critical to understand the chemical nature of these materials to select optimum conditions for ligand immobilization. In this chapter, we have explained some commonly employed ligand immobilization techniques to graft the ligand on the resin surfaces.

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Article Synopsis
  • Monoclonal antibodies (mAbs) are vital for treatments and diagnostics in medicine, but their high cost, especially for cancer therapies, poses significant challenges.
  • A new synthesis method for low-cost, reusable Protein A (PrA)-like nanoparticles (NPs) is proposed, which improves the purification process for IgG antibodies, crucial for mAb production.
  • The study demonstrates that these innovative NPs can outperform traditional PrA resins in binding efficiency and cost-effectiveness, allowing for at least 15 reuses at a fraction of the expense, making them a promising alternative in immunotherapy.
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