Publications by authors named "C K Chambliss"

Article Synopsis
  • Harmful cyanobacterial blooms are increasingly threatening water quality, prompting a study on the interactions between nitrogen-fixation and toxin production in cyanobacteria.
  • A gradient of nitrogen to phosphorus resources was tested, revealing that low nitrogen to phosphorus (N:P) cultures can match the biomass of high N:P cultures without a tradeoff in nitrogen fixation.
  • The results suggest two functional groups among nitrogen-fixing cyanobacteria—N-storage-strategists and growth-strategists—that influence bloom size and toxin production in environmental settings.
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Freshwater ecosystems are experiencing increased salinization. Adaptive management of harmful algal blooms (HABs) contribute to eutrophication/salinization interactions through the hydrologic transport of blooms to coastal environments. We examined how nutrients and salinity interact to affect growth, elemental composition, and cyanotoxin production/release in two common HAB genera.

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Objectives: Individuals with sickle cell disease (SCD) are at severely heightened risk for cerebrovascular injury and acute cerebrovascular events, including ischemic and hemorrhagic stroke, potentially leading to impaired development and life-long physical and cognitive disabilities. Cerebrovascular injury specific to SCD includes inflammation caused by underlying conditions of chronic hemolysis and reduced cerebrovascular perfusion. The objectives of this study were to investigate whether expression of neuregulin-1β (NRG-1), an endogenous neuroprotective polypeptide, is increased in SCD or experimental conditions mimicking the hemolysis and ischemic conditions of SCD, and to determine if treatment with exogenous NRG-1 reduces markers of cerebrovascular inflammation.

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Wastewater-based epidemiology (WBE) provides an early warning and trend analysis approach for determining the presence of COVID-19 in a community and complements clinical testing in assessing the population level, even as viral loads fluctuate. Here, we evaluate combinations of two wastewater concentration methods (i.e.

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Brain is inhomogeneous due to its composition of different tissue types (gray and white matter), anatomical structures (e.g. thalamus and cerebellum), and cavities in the brain (ventricles).

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