Managing medicines-related continuity of care: the views of a range of prescribers in New Zealand general practice.

Introduction Continuity of care is considered vital to achieving high-quality health care. Traditionally, general practitioners have played a key role in managing continuity of care and have largely been accountable for prescribing decision-making in primary care. Following prescribing legislation changes, a range of health disciplines make decisions regarding medicines in the general practice setting.

Pathways From Poverty to Child Mental Health in Burkina Faso: Longitudinal Mediation Analyses in a Cluster-Randomized Clinical Trial.

Purpose: The study applies the Family Stress Model to examine the impact of an integrated intervention on the mental health of children facing chronic adversity in Burkina Faso. Its primary goal is to enhance understanding of individual and relational factors at the family level as mediators and specific mechanisms through which poverty reduction can impact child well-being.

Methods: Cross-lagged autoregressive longitudinal mediation analyses tested the intervention effect on child mental health, examining maternal depression, maternal anxiety, harsh parenting, and child exposure to abuse as potential mediators.

Phase Partitioning of the Neutrophil Oxidative Burst is Coordinated by Accessory Pathways of Glucose Metabolism and Mitochondrial Activity.

Neutrophils are a part of the innate immune system and produce reactive oxygen species (ROS) to extinguish pathogens. The major source of ROS in neutrophils is NADPH oxidase, which is fueled by NADPH generated via the pentose phosphate pathway; however, it is unclear how other accessory glucose metabolism pathways and mitochondrial activity influence the respiratory burst. We examined the temporal dynamics of the respiratory burst and delineated how metabolism changes over time after neutrophil activation.

Postoperative outcomes in colorectal surgery by day of surgery: A national cohort study.

Aim: Poorer postoperative outcomes have been observed for patients admitted and operated on later in the week and over the weekend. This is thought to be related to temporal fluctuations in the quality of perioperative care. The aim of this work was to identify if the day of surgery influenced outcomes in a national cohort of colorectal cancer (CRC) resections.

Cognition in Meningioma: Effects of Tumor Location and Tumor Removal.

Background: Meningiomas are the most common type of primary intracranial tumor, yet very few studies have assessed the effects of tumor removal.

Methods: Here we report analysis of patients with meningiomas who underwent routine neuropsychological assessment and surgery at a National Health Service (NHS) hospital in the North East of England over a 6-year period.

Results: Surgical removal of tumors significantly improved both phonemic and semantic verbal fluency and some measures of working memory and declarative memory.