Publications by authors named "C Juan"
Mycotoxins pose significant health risks due to their prevalence in food products and severe health implications, including carcinogenicity. This study investigates the bioavailability of mycotoxins aflatoxin B1 (AFB1), ochratoxin A (OTA), and zearalenone (ZEN) individually and combined, in the presence of identified polyphenols from tiger nut beverage (TNB) and tiger nut by-product (TNBP) using the in vitro model Caco-2 cells, which simulates the human intestinal barrier. The objective is to understand how bioactive compounds from TNBP can mitigate the effects of AFB1, OTA and ZEN (and their combination) by bioavailability interference, contributing to safer food products and innovative food safety strategies.
View Article and Find Full Text PDFPrevious research demonstrated that transcranial alternating current stimulation (tACS) can induce phosphene perception. However, tACS involves rhythmic changes in the electric field and alternating polarity (excitatory vs. inhibitory phases), leaving the precise mechanism behind phosphene perception unclear.
View Article and Find Full Text PDFThe emergence of new psychoactive substances (NPS) in the global drug market since the 2000s has posed major challenges for regulators and law enforcement agencies. Among these, synthetic cathinones have gained prominence due to their stimulant effects on the central nervous system, leading to widespread recreational use. These compounds, often marketed as alternatives to illicit stimulants such as amphetamines and cocaine, have been linked to numerous cases of intoxication, addiction and death.
View Article and Find Full Text PDFBackground: Patients with Parkinson's disease (PD) present progressive deterioration in both motor and non-motor manifestations. However, the absence of clinical biomarkers for disease progression hinders clinicians from tailoring treatment strategies effectively.
Objectives: To identify electroencephalography (EEG) biomarker that can track disease progression in PD.
Dupilumab impact on psychiatric and sleep disorder risk reduction in atopic dermatitis: A population-based cohort study.
Ann Allergy Asthma Immunol
November 2024
Article Synopsis
- - Patients with atopic dermatitis (AD) are at higher risk for psychiatric and sleep disorders, prompting a study to compare the risks between those treated with dupilumab and conventional drugs.
- - The study analyzed 12,228 adult patients, showing that those on dupilumab had significantly lower risks of anxiety, depressive disorders, adjustment disorders, and sleep disorders compared to those on conventional treatments, though ADHD risk remained unchanged.
- - Findings suggest that dupilumab may be particularly beneficial for reducing psychiatric and sleep disorder risks in AD patients, especially among Black or African American individuals.