Publications by authors named "C Joens"

Article Synopsis
  • Rastelli surgery is performed to correct congenital heart defects, but late-onset cardiac arrhythmias are a notable complication, and there's limited data on their occurrence after this surgery.
  • In a study of 55 patients followed for over 24 years, 38.4% experienced tachyarrhythmias, with older age at surgery linked to a higher risk; 21.8% had bradyarrhythmias, and some required catheter ablation.
  • The results indicate that arrhythmia prevalence is significant and increases with age post-surgery, emphasizing the need for long-term monitoring in patients who underwent Rastelli surgery.
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Aims: Electroanatomical maps using automated conduction velocity (CV) algorithms are now being calculated using two-dimensional (2D) mapping tools. We studied the accuracy of mapping surface 2D CV, compared to the three-dimensional (3D) vectors, and the influence of mapping resolution in non-scarred animal and human heart models.

Methods And Results: Two models were used: a healthy porcine Langendorff model with transmural needle electrodes and a computer stimulation model of the ventricles built from an MRI-segmented, excised human heart.

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Article Synopsis
  • Conventional mapping of focal ventricular arrhythmias has limitations because unipolar electrogram characteristics and local activation times often fail to accurately indicate the site and depth of these arrhythmias, especially deep intramural foci.
  • An experimental study using swine hearts and custom electrode arrays showed that common unipolar patterns are not reliable for identifying superficial arrhythmic sources as depth increases, leading to potential misplacement during treatment.
  • The research suggests that while traditional mappings fall short, new surface indices can improve the accuracy of determining the depth of arrhythmic foci, enhancing treatment strategies for better outcomes in arrhythmia management.
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Background: Atrial tachyarrhythmias (AAs) are the main source of morbidity and mortality in adult congenital heart disease (ACHD). Direct-current cardioversion (DCCV) is an effective method to acutely terminate AAs, but many patients require repeated DCCV. Little is known about the impact of radiofrequency catheter ablation (RFCA) of AAs on the incidence of repeated DCCV in patients with ACHD.

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Background: The prevalence of diabetes mellitus (DM) and ischemic heart disease is increasing. Moreover, patients with DM experiencing an acute coronary syndrome (ACS) have an increased risk of adverse outcomes after revascularization compared to non-diabetics. Data have suggested that the glycoprotein IIb/IIIa inhibitor abciximab might be more efficient in diabetics than in those without DM.

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