Publications by authors named "C Jacomet"
Background: Despite vaccination, patients receiving anti-CD20 monoclonal antibodies (mAbs) for multiple sclerosis (MS) or neuromyelitis optica spectrum disorders (NMOSD) have an increased risk of developing severe or protracted COVID-19. The aim of this study was to describe the effect of COVID-19 convalescent plasma (CCP) in patients with MS or NMOSD exposed to anti-CD20 and infected by SARS-CoV-2.
Methods: This French national, retrospective cohort study was conducted between November 2020 and June 2023.
Access to dental care is still complex in 2022 for patients living with HIV despite the need for careful monitoring of pathologies of the oral mucosa. Results of a monocentric cross-sectional study in the Infectious Diseases Department of Clermont-Ferrand University Hospital.
Clin Oral Investig
December 2023
Objectives: Describe the dental care pathway of people living with HIV (PLHIV) and their oral pathologies.
Materials And Methods: A monocentric cross-sectional study involving adult PLHIVs followed (October 2021/April 2022) in our department. Socio-demographic and medical data, course of dental care, and presence of pathologies of the oral mucosa were recorded.
Article Synopsis
- - The study evaluated the effectiveness of a nationwide anal cancer screening program for high-risk HIV patients in France, focusing on adherence to the program and cancer diagnosis rates.
- - Out of 700 patients, those with higher grades of anal intra-epithelial neoplasia (AIN) faced significantly increased risks of developing anal cancer, but strict adherence to screening (only 4.6% of participants) did not show a decrease in cancer risk.
- - Despite not diagnosing any anal cancer among adherent patients, the screening led to more frequent diagnoses of anal warts, indicating a need for further investigation into the program's actual impact on cancer risk reduction.
Article Synopsis
- * The occurrence of HLA-B*57:01 was similar in patients with PML (6.19%) and those without (5.08%), indicating no significant difference.
- * Clinical and biological characteristics, as well as outcomes for PML, were unaffected by the HLA-B*57:01 status among those diagnosed with PML.
Introduction: Pre-exposure prophylaxis (PrEP) is a combination of antiretroviral regimen, tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) that has been shown to prevent HIV transmission. It had been regulated through a temporary recommendation use since December 2015 and had marketing authorization in France since March 2017. As, this product is proposed for adults and adolescents safe from HIV but at high risk of infection, the question is to know if there is a safety concern about this use.
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