Publications by authors named "C J Waitt"
Background: Appropriate language use is essential to ensure inclusion of diverse populations in research. We aimed to identify possible language-related barriers regarding the informed consent process and propose interventions to improve clarity and understanding of pregnant and breastfeeding women participating in research.
Methods: A cross-sectional qualitative study employing focus group discussions (FGD) was conducted in Uganda from August 2023 to September 2023, involving a diverse group of stakeholders from the community, including community members, research participants, and Community Advisory Board members.
Advancing pharmacometrics in Africa-Transition from capacity development toward job creation.
CPT Pharmacometrics Syst Pharmacol
December 2024
Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high-income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention. We review the APT program's progress over 3 years and encourage collaboration to enhance local clinical data analysis in Africa.
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- Caesarean sections (CS) are the most common major surgery worldwide, but they pose significant risks for maternal mortality, especially in low-resource settings like Malawi, where a study reviewed maternal deaths from 2020 to 2022.
- The study found that over half of maternal deaths (51.8%) occurred after CS, with women undergoing CS being five times more likely to die compared to those who delivered vaginally, due to causes like postpartum hemorrhage, eclampsia, and infection.
- Health system issues contributed to these deaths, including delayed treatment and inadequate monitoring, indicating a pressing need to enhance the safety and management of CS in healthcare practices.