Publications by authors named "C J Van-der Hofstadt Roman"
Objectives: The aim of the present study was to quantify research outputs after completing a Coursework Pathway (CP).
Methods: Emergency medicine trainees who completed a CP during 2012-2022 were included. Research outputs were identified using Medline, EMBASE, Pubmed and Google Scholar.
Intracerebral hemorrhage (ICH) presents complex clinical challenges, particularly in patients receiving anticoagulation therapy. This case report discusses the management of acute ICH in a 60-year-old male patient on long-term apixaban therapy, who arrived at the emergency department with altered consciousness, right-sided hemiplegia, and mixed aphasia. Computed tomography (CT) imaging revealed a 70 ml left lenticular-capsular hematoma with significant mass effect, necessitating rapid intervention.
View Article and Find Full Text PDFBackground: Blood pressure (BP) control following stroke is important but currently sub-optimal. This trial aimed to determine whether self-monitoring of hypertension with telemonitoring and a treatment escalation protocol, results in lower BP than usual care in people with previous stroke or transient ischaemic attack (TIA).
Methods: Unblinded randomised controlled trial, comparing a BP telemonitoring-based intervention with control (usual care) for hypertension management in 12 primary care practices in England.
Despite its wide use to treat various inflammatory diseases, infliximab becomes ineffective in some patients due to inadequate drug levels and production of anti-drug antibodies (ADA). The aim of this study was to compare the prevalence and ADA levels in a large cohort of patients ADA and IFX through levels measured by ELISA were collected from 505 patients within a period of four years. The results indicate that i) 13.
View Article and Find Full Text PDFArticle Synopsis
- Life cycle assessment (LCA) is crucial for developing sustainable technologies, particularly in evaluating bioplastics made from orchard waste.
- Bioplastics like L-polylactic acid (PLA) and poly(3-hydroxybutyrate) (PHB) are promising substitutes for traditional plastics due to their biodegradability and non-toxicity.
- LCAs revealed that the most environmentally impactful stages for both PLA and PHB production are the initial processes of biomass processing and pretreatment, which are energy-intensive and contribute significantly to CO emissions.