Updating Normal Organ Weights Using a Large Current Sample Database.

Context.—: Organ weights are an essential part of autopsy analysis. Deviations from normal organ weights provide important clues to disease processes.

Toxic Injury to the Gastrointestinal Tract After Ipilimumab Therapy for Advanced Melanoma.

Ipilimumab, cytotoxic T-lymphocyte-associated protein 4-blocking antibody, is known to precipitate tissue-specific immune-related adverse events. The second most common site for immune-related adverse events is the gastrointestinal tract, with toxic injury resulting in diarrhea, colitis, and enterocolitis. In the present case, a woman who received ipilimumab 2 weeks prior was found to have severe, diffuse corticosteroid-refractory gastrointestinal tract toxic injury affecting the stomach, small bowel, and colon.

Urethral obstruction by seminal coagulum is associated with medetomidine-ketamine anesthesia in male mice on C57BL/6J and mixed genetic backgrounds.

Male and female mice were anesthetized by intraperitoneal injection with a mixture delivering 0.5 mg/kg medetomidine and 50 mg/kg ketamine to achieve immobilization for whole-body radiographs and bone densitometry, as part of a phenotypic screen for bone and mineral disorders in mice carrying genetic modifications induced through mutagenesis with N'-ethyl-N'-nitrosourea. Morbidity and mortality occurred in 19 of 628 (3%) of male mice 24 to 72 h after a seemingly uneventful recovery from anesthesia.

Comparison of attitudes between Generation X and Baby Boomer veterinary faculty and residents.

Understanding the characteristics and preferences of the different generations in the veterinary workforce is important if we are to help optimize current and future veterinary schools and teaching hospitals. The purpose of this study was to compare the attitudes of different generations of veterinary faculty and those of faculty and house officers. A survey administered to faculty and house officers asked respondents to identify their level of agreement with a series of statements addressing work and lifestyle issues and feedback preferences.