Dysfunction of transcallosally mediated motor inhibition and callosal morphology in patients with schizophrenia.

Objective: In order to assess the functional integrity of motor pathways through the corpus callosum (CC) in patients with schizophrenia transcallosally mediated inhibition (TI) of voluntary tonic EMG activity of first dorsal interosseus muscle following ipsilateral focal transcranial magnetic stimulation (fTMS) was investigated. In addition thickness and length of CC were calculated.

Method: Twelve patients suffering from schizophrenia and 12 healthy controls were investigated.