Integrated Analysis of Methylome and Transcriptome Responses to Exercise Training in Children with Overweight/Obesity.

We examined the effects of a 20-week exercise intervention on whole-blood genome-wide DNA methylation signature and its association with the exercise-induced changes in gene expression profiles in boys and girls with overweight/obesity (OW/OB). Twenty-three children (10.05 ± 1.

Cumulative effects of H and P on force and power of skeletal muscle fibres from young and older adults.

The cellular causes of the age-related loss in power output and increased fatigability are unresolved. We previously observed that the depressive effects of hydrogen (H) (pH 6.2) and inorganic phosphate (P) (30 mm) did not differ in muscle fibres from young and older men.

Life cycle assessment of biochar filters for on-site wastewater treatment.

Biochar is a promising filter material for wastewater treatment. This study evaluated the environmental (climate, eutrophication, acidification) impacts of biochar filters for onsite wastewater treatment and compared them with those of a conventional sand filter. Using a parameterised life cycle assessment (LCA) approach, these three impact categories were quantified for two designs of biochar filter and a sand filter, used in normal and sensitive areas as defined by Swedish government recommendations.

Myocardial blood flow in newly diagnosed breast cancer patients at rest and during exercise.

The heart depends critically on continuous blood supply, but it is unknown whether cancer itself affects myocardial blood flow (MBF). This study investigated MBF in cancer patients and cardiac morphology in a cancer mice model. MBF was quantified with [O]HO positron emission tomography at rest in recently diagnosed breast cancer patients and age-matched female controls, and additionally during 10-min exercise in the cancer patients.