Function of Cytochrome P450 CYP72A1182 in Metabolic Herbicide Resistance Evolution in Amaranthus palmeri Populations.

Evolution of metabolic herbicide resistance is a major issue for weed management. Few genes and regulatory mechanisms have been identified, particularly in dicotyledonous weed species. We identified putative causal genes and regulatory mechanism for tembotrione-resistance in Amaranthus palmeri.

Improving Respite Outcomes for Caregivers: Who Benefits and Under What Conditions?

Alzheimer's disease and related dementias (ADRD) pose a substantial caregiving burden in the United States, yet efforts to improve caregiver well-being have seen mixed results. We ask whether an app-based intervention ( = 143) to prioritize can substantially improve the caregiving experience, and whether these benefits are moderated by (1) caregiver demographics and (2) conditions of the caregiving situation (such as baseline impairment). Constructing curvilinear growth models to assess changes over a 20-week period, we find significant improvements in the positive aspects of caregiving (PAC).

The role of nutrition in wound healing and implications for nursing practice.

Nutrition plays a vital role in wound healing, influencing both the speed and quality of recovery. The wound healing process encompasses haemostasis, inflammation, proliferation, and remodelling, each reliant on specific nutrients. This article summarises the current literature on the role of nutrition in wound healing, focusing on key nutrients: proteins, vitamins (A, C, E, K), and minerals (zinc, iron, copper, manganese), essential for collagen synthesis, immune function, and cellular activity.

Twelve-month results for a randomized sham-controlled effectiveness trial of an in-home skills-based virtual reality program for chronic low back pain.

Introduction: Low-risk, accessible, and long-term effective nonpharmacologic behavioral interventions for chronic low back pain (cLBP) are needed. Pain education and cognitive behavioral therapy (CBT) are recommended first-line treatments, but access is poor, treatment effectiveness is variable, and long-term effectiveness is inconsistent. In-home virtual reality (VR)-delivered therapies might address these shortcomings because therapeutic content can be delivered in a consistent and quality-controlled manner.

Inadequate Performance of ChatGPT on Orthopedic Board-Style Written Exams.

Background: Chat Generative Pre-Trained Transformer (ChatGPT) is an artificial intelligence (AI) chatbot capable of delivering human-like responses to a seemingly infinite number of inquiries. For the technology to perform certain healthcare-related tasks or act as a study aid, the technology should have up-to-date knowledge and the ability to reason through medical information. The purpose of this study was to assess the orthopedic knowledge and reasoning ability of ChatGPT by querying it with orthopedic board-style questions.