Publications by authors named "C J Sheu"
For investigating the host response in associated pneumonia, we analyzed the host genetic sequences obtained from metagenomic next-generation sequencing (mNGS). The samples for mNGS were bronchoalveolar lavage fluid (BALF) collected from the lungs of patients infected with and from patients without bacterial infections. BALF samples from patients with pneumonia were collected from the lungs of patients infected with with New Delhi metallo-β-lactamase (NDM, before treatment), A.
View Article and Find Full Text PDFMechanical power (MP) refers to ventilator-delivered energy to the lungs, which may induce lung injury. We examined the relationship between MP and mortality in patients with acute respiratory distress syndrome (ARDS) who underwent prone positioning. This multicenter retrospective study included data on all patients admitted to the intensive care units of eight referral hospitals in Taiwan from October 2015 to March 2016, and in Chang Gung Memorial Hospital Linkou branch from January 2017 to October 2023.
View Article and Find Full Text PDFBackground: This study aimed to assess the diagnostic and prognostic value of Aspergillus-specific IgG (Asp-IgG) for invasive pulmonary aspergillosis (IPA) in non-neutropenic non-hematologic patients.
Methods: Between November 2019 and February 2022, we recruited 40 non-neutropenic, non-hematologic IPA patients from Taiwan and measured serum Asp-IgG levels using Phadia, Thermofisher. A positive Asp-IgG test was defined as a level > 40 mgA/L.
Article Synopsis
- Idiopathic pulmonary fibrosis (IPF) is a severe lung disease with limited treatments, and pirfenidone has been approved for its treatment in Taiwan since 2016.
- A study was conducted on 50 IPF patients in Taiwan to assess the real-world safety and effectiveness of pirfenidone, revealing that most patients showed no significant changes in lung function or walking distance after treatment, although pirfenidone did help stabilize cough symptoms.
- The study found that while 62% of patients experienced side effects, with decreased appetite being most common, overall, pirfenidone was considered an effective and safe option for IPF treatment in this population.
Background: Patients with advanced heart failure (AHF) desire communication around values and goals prior to treatment decisions.
Objectives: To evaluate the timing and content of the first serious illness communication (SI conversation) for patients with AHF after referral to a specialist palliative care (PC) team (HeartPal).
Methods: In this retrospective cohort study, we used electronic health records to identify patients referred to HeartPal and their first SI conversations at a tertiary care hospital between October 2018 and September 2021.