Publications by authors named "C J Shanley"

Article Synopsis
  • POEMS syndrome is a rare condition caused by problems in plasma cells and has five main features: nerve issues, organ enlargement, hormone problems, a specific type of protein in the blood, and skin changes.
  • In a study that included 46 patients from Latin America, researchers found that all had nerve problems, and many had skin changes and organ enlargement, with a median time of 7.7 months to get diagnosed.
  • The survival rate for patients was really good, with all patients who had a transplant still alive, suggesting that treatment in Latin America is effective and similar to other parts of the world.
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Article Synopsis
  • 3D structured light scanning is a useful tool in forensic anthropology for creating accurate models of skeletal remains, which aids in analysis, data sharing, and legal presentations without risking damage to originals.
  • The study evaluates the accuracy of 3D scans and prints for ten different bone types by comparing standard measurements from physical bones, virtual models, and printed versions, using specific statistical methods to quantify errors.
  • Results show that measurements from virtual models and prints are generally accurate (within ±2 mm), but some bones were less reliable for specific measurements; overall, the technique meets acceptable standards for forensic analysis.
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Development of novel medical devices for the treatment of musculoskeletal pain associated with neuro-muscular trigger points requires a model for relating the mechanical responses of in vivo biological tissues to applied palliative physical pressures and a method to design treatments for optimal effects. It is reasonable to hypothesize that the efficacy of therapeutic treatment is proportional to the maximum tensile strain at trigger point locations. This work presents modeling of the mechanical behavior of biological tissue structures and treatment simulations, supported by indentation experiments and finite element (FE) modeling.

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Purpose: Multiple myeloma (MM) is a highly heterogeneous, incurable disease most frequently diagnosed in the elderly. Therefore, data on clinical characteristics and outcomes in the very young population are scarce.

Patients And Methods: We analyzed clinical characteristics, response to treatment, and survival in 103 patients with newly diagnosed MM age 40 years or younger compared with 256 patients age 41-50 years and 957 patients age 51 years or older.

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This article describes our experience developing a novel mobile health unit (MHU) program in the Detroit, Michigan, metropolitan area. Our main objectives were to improve healthcare accessibility, quality and equity in our community during the novel coronavirus pandemic. While initially focused on SARS-CoV-2 testing, our program quickly evolved to include preventive health services.

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