Publications by authors named "C J Seow"

Introduction: Children born to women with inflammatory bowel disease (IBD) may have increased health care utilization in early life due to genetic susceptibilities and exposure to inflammation in utero, although this has not been robustly evaluated. We aimed to characterize health care use between these groups.

Methods: We accessed province-wide health administrative databases to identify children born to women with and without IBD between 2002 and 2019.

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Article Synopsis
  • There are many treatment options for inflammatory bowel disease (IBD), but the current standard doses often don't meet the desired results, highlighting the need to improve existing therapies instead of only focusing on new ones.
  • The article emphasizes the use of therapeutic drug monitoring (TDM) to enhance the effectiveness of biologic therapies, particularly for TNF inhibitors, by measuring drug levels and identifying immune reactions.
  • By optimizing dosages and maintaining appropriate drug levels, patients have a better chance of achieving sustained clinical remission beyond just symptom management.
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Background/objective: Non-islet cell tumor hypoglycemia (NICTH) is an uncommon condition, of which only a few cases caused by malignant phyllodes tumor of the breast have been reported. We describe a case of NICTH secondary to malignant phyllodes tumor with good response to glucocorticoid therapy.

Case Report: A 62-year-old woman with a rapidly enlarging left breast mass presented with drowsiness and a capillary blood glucose level of 32.

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Introduction And Objectives: There are limited recent data on the burden of chronic hepatitis B (CHB) in the North American general population. We aimed to identify the CHB burden from a Canadian population-based perspective.

Patients And Methods: Using a retrospective cohort design, we searched Alberta Analytics administrative databases including the Provincial Laboratory database, to describe CHB epidemiology and natural history in Alberta, Canada between fiscal years 2012-2020.

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