Publications by authors named "C J Ocadaque"
Article Synopsis
- The article investigates the use of carbonyl cyanide m-chlorophenyl hydrazone (CCCP) as an efflux pump inhibitor to combat antimicrobial resistance and biofilm formation.
- It found that CCCP significantly reduces biofilm biomass and enhances the effectiveness of antibiotics against biofilms when used at certain concentrations (128 µM and 512 µM).
- CCCP also impacts the production of virulence factors, decreasing protease production and increasing siderophore release, indicating its potential as a therapeutic aid in managing infections related to biofilms.
This study evaluated the antimicrobial activity of promethazine against , and and its effect on the antimicrobial susceptibility of biofilms grown and on porcine heart valves. Promethazine was evaluated alone and in combination with vancomycin and oxacillin against spp. and vancomycin and ceftriaxone against in planktonic form and biofilms grown and .
View Article and Find Full Text PDFFreshwater cetaceans play a significant role as sentinel animals, providing important data on animal species and aquatic ecosystem health. They also may serve as potential reservoirs of emerging pathogens and host virulence genes in their microbiota. In this study, we evaluated virulence factors produced by Gram-negative bacteria recovered from individuals belonging to two populations of free-ranging Amazon river dolphins (Inia geoffrensis).
View Article and Find Full Text PDFPyometra is one of the most common diseases in adult female dogs, characterized by a suppurative bacterial infection of the uterus with accumulation of inflammatory exudate and a variety of local and systemic clinical manifestations. This study aimed to identify the bacteria within the uterine content and vaginal canal of bitches with pyometra and evaluate their antimicrobial susceptibility and production of virulence factors. Uterine and vaginal content were collected with sterile swabs from 30 bitches diagnosed with pyometra.
View Article and Find Full Text PDFStudies on the microbiota of freshwater cetaceans are scarce and may provide important data on animal and environmental health. This study aimed to evaluate the antimicrobial susceptibility of Gram-negative bacteria recovered from two populations of free-ranging Amazon river dolphins (Inia geoffrensis). Twenty-one animals were captured and released, 13 from Negro River and 8 from Tapajós River, Brazil.
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