Addressing various dimensions of well-being can help improve oncology patients' symptoms and their overall quality of life (QOL); similar strategies can be used to support caregivers of oncology patients to improve not only QOL of the caregiver, but the patient. Beyond patient and caregiver support, interventions focusing on dimensions of well-being can improve the culture of wellness, practice efficiency, and enhance personal resilience among oncology providers to mitigate burnout. Herein, the authors discuss multiple evidence-based strategies to improve well-being of oncology patients, caregivers, and providers.
View Article and Find Full Text PDFIntroduction: This study sought to describe treatment patterns, persistence, and effectiveness of upadacitinib (UPA) alone and compared to other Janus kinase inhibitors (JAKis) or tumor necrosis factor inhibitors (TNFis) in patients with rheumatoid arthritis (RA).
Methods: This retrospective, non-interventional study used the OPAL dataset, derived from electronic medical records. Patients initiated UPA (N = 2624), other JAKis (baricitinib and tofacitinib [N = 925]), or TNFis (adalimumab, etanercept, certolizumab, golimumab, infliximab [N = 3540]) between May 2020 and March 2023.
Controlled environment farming (CEF) systems, including tunnel houses, glasshouses, and vertical farms, are expanding worldwide. As the industry scales, growers need a broader range of crops that are adapted to CEF systems to take full advantage of the potential to increase yields and decrease weather-related risks. Dwarf grapevines (microvines) are ideal candidates for CEF due to their high economic value, phenotype, and phenology.
View Article and Find Full Text PDFThe National Center for Biotechnology Information (NCBI) provides online information resources for biology, including the GenBank® nucleic acid sequence repository and the PubMed® repository of citations and abstracts published in life science journals. NCBI provides search and retrieval operations for most of these data from 31 distinct repositories and knowledgebases. The E-utilities serve as the programming interface for most of these.
View Article and Find Full Text PDFPurpose: This study evaluates real-world outcomes, toxicities, and prescribing patterns of PARP inhibitors (PARPis) for the treatment of metastatic breast cancer (MBC).
Patients And Methods: Electronic health records of 62 MBC patients treated with olaparib (n = 48) or talazoparib (n = 14) at Mayo Clinic System between 2017 and 2022 were analyzed. Time-to-treatment-failure (TTF) was assessed utilizing the Kaplan-Meier method.