Publications by authors named "C J Langevin"
Article Synopsis
- Fluorescent molecules are essential in biomedicine for visualizing biological processes with high sensitivity and specificity, but customizing them for live cell imaging is challenging due to complex structural and photophysical interactions.
- This study used multivariate linear free-energy relationships (mLFER) to optimize a new platform of fluorescent dyes called BASHY, which are derived from boronic acid and salicylidenehydrazone.
- The research resulted in a predictive model for a novel BASHY dye, which demonstrated effective stability in live cell experiments and was tested successfully in zebrafish larvae.
Spring viremia of carp virus (SVCV) has a broad fish host spectrum and is responsible for a disease that generally affects juvenile fishes with a mortality rate of up to 90%. In the absence of treatments or vaccines against SVCV, the search for prophylactic or therapeutic solutions is thus relevant, particularly to identify solutions compatible with mass vaccination. In addition to being a threat to aquaculture and ecosystems, SVCV is a unique pathogen to study virus-host interactions in the zebrafish model.
View Article and Find Full Text PDFWith the increasing occurrence and severity of cyanobacterial harmful algal blooms (cHAB) at the global scale, there is an urgent need for rapid, accurate, accessible, and cost-effective detection tools. Here, we detail the RosHAB workflow, an innovative, in-the-field applicable genomics approach for real-time, early detection of cHAB outbreaks. We present how the proposed workflow offers consistent taxonomic identification of water samples in comparison to traditional microscopic analyses in a few hours and discuss how the generated data can be used to deepen our understanding on cyanobacteria ecology and forecast HABs events.
View Article and Find Full Text PDFAn agricultural water use package has been developed for MODFLOW 6 using the MODFLOW Application Programming Interface (API). The MODFLOW API Agricultural Water Use Package (API-Ag) was based on the approach to simulate irrigation demand in the MODFLOW-NWT and GSFLOW Agricultural Water Use (AG) Package. The API-Ag Package differs from the previous approach by implementing new features and support for additional irrigation providers.
View Article and Find Full Text PDFMODFLOW 6 is the latest in a line of six "core" versions of MODFLOW released by the U.S. Geological Survey.
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