Publications by authors named "C J Inchley"
Objective: There is conflicting evidence whether subtypes of Respiratory syncytial virus have different seasonality or are differentially associated with clinical severity. We aimed to explore the associations between disease severity and RSV subtypes RSV-A and RSV-B and to describe the circulation of RSV subtypes pattern by season and age.
Methods: Active prospective hospital surveillance for RSV-A and RSV-B in children <59 months of age was conducted during 2015-2018.
Objective: To evaluate risk factors for severe disease in children under 59 months of age hospitalized with respiratory syncytial virus (RSV) infection.
Study Design: We prospectively enrolled 1,096 cases of laboratory confirmed RSV infection during three consecutive RSV seasons in 2015-2018. Potential risk factors for severe disease were retrieved through patient questionnaires and linkage to national health registries.
Article Synopsis
- The study aimed to estimate the incidence of respiratory syncytial virus (RSV) infections in hospitalized children under 59 months old in Norway and analyze the disease's epidemiology.
- Active surveillance was conducted from 2015 to 2018, enrolling febrile children aged 12-59 months and younger children based on respiratory symptoms, linking data to national registries to assess the clinical burden of RSV.
- Out of 2,745 enrolled children, 40% were found to be infected with RSV, with the highest incidence in infants, particularly 1 month old, during the 2016-2017 peak season; most infected children were previously healthy, although those with pre-existing conditions experienced higher hospital contact rates