Publications by authors named "C J Hsueh"
Oral cavity squamous cell carcinoma (OSCC), a leading subtype of head and neck cancer, exhibits high global incidence and mortality rates. Despite advancements in surgery and radiochemotherapy, approximately one-third of patients experience relapse. To improve current targeted and immunotherapy strategies for recurrent OSCC, we conducted multi-omics analyses on pretreatment OSCC samples (cohorts 1 and 2, n=137) and identified A3A and EGFR, both at the RNA and protein levels, as inversely expressed markers for patient stratification and response prediction.
View Article and Find Full Text PDFBackground: Lymph node ratio (LNR), log odds of positive lymph nodes (LODDS), and the number of postoperative lymph node staging (pN) are prognostic indicators of various cancers. However, the prognostic values of these indicators remain unclear in hypopharyngeal squamous cell carcinoma (HPSCC). This study's primary objective was to investigate the predictive value of LNR, LODDS, and pN for advanced HPSCC, and the secondary objective was to compare which of the values had the best predictive value for advanced HPSCC.
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- The study investigates the effects of caffeine supplementation on performance metrics in collegiate male rugby sevens players during two-day tournaments.
- Participants were monitored for various physical performance aspects, including distance traveled at different speeds and reactive agility, using global positioning systems.
- Results showed caffeine improved jogging distance and reactive agility compared to a placebo, suggesting caffeine can enhance certain performance attributes in rugby sevens.
High mortality in bobwhite quail chicks () (35%-85%) was reported from a grower flock in Iowa during July and August of 2022. Two diagnostic submissions of dead, 3-day-old quail chicks were received. Postmortem examination revealed multifocal, pinpoint, pale tan foci in the liver of all birds.
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- Asian individuals are at a higher risk for gestational diabetes in the U.S., with a notable prevalence rate of 12.3% among Asian pregnancies compared to 6.5% overall.
- Data indicates that prepregnancy hypertension increases this risk significantly, with 29.3% of hypertensive Asian subjects affected.
- There are considerable differences in gestational diabetes risk across various Asian subgroups, emphasizing the necessity for personalized screening and interventions based on specific ancestry and maternal nativity.