Publications by authors named "C J Heneghan"
Circadian rhythms are governed by a biological clock, and are known to occur in a variety of physiological processes. We report results on the circadian rhythm of heart rate observed using a wrist-worn wearable device (Fitbit), consisting of over 17,000 individuals over the course of 30 days. We obtain an underlying heart rate circadian rhythm from the time series heart rate by modeling the circadian rhythm as a sum over the first two Fourier harmonics.
View Article and Find Full Text PDFAim: Local excision (LE) for T1 rectal cancer may be recommended in those with low-risk disease, while resection is typically recommended in those with a high risk of luminal recurrence or lymph node metastasis. The aim of this work was to compare survival between resection and LE.
Method: This was a population-based retrospective cohort study set in the Canadian province of Ontario.
Article Synopsis
- * A total of 13 studies involving 229 COVID-19 patients were analyzed, revealing that only six of 308 faecal samples (1.9%) contained replication-competent SARS-CoV-2.
- * The review concludes that while the presence of the virus in faeces is biologically possible, there is currently no direct evidence of oro-faecal transmission to humans, emphasizing the need for further standardized research to clarify this potential route.
Objective: The primary objective was to investigate temporal trends and between-practice variability of paediatric test use in primary care.
Methods And Analysis: This was a descriptive study of population-based data from Clinical Practice Research Datalink Aurum primary care consultation records from 1 January 2007 to 31 December 2019. Children aged 0-15 who were registered to one of the eligible 1464 general practices and had a diagnostic test code in their clinical record were included.
Aim: To describe where clinical information is contemporarily and commonly found in UK primary care, what is favoured by clinicians, and whether this is (1) publicly funded (2) has commercial potential conflicts of interest.
Design And Setting: A mixed methods study, consisting of (1) site visits to general practices in Scotland, (2) online questionnaire, focused on UK general practice (3) analysis of materials cited by professionals.
Methods: Data about sources of clinical information used was obtained verbally, visually and via search histories on computers from visits.