Publications by authors named "C J Gallione"
Maintaining good oral hygiene is essential for preventing and managing oral health problems. This systematic review aimed to identify and assess clinical practice guidelines on oral hygiene, focusing on quality and key areas. A comprehensive search was conducted in PubMed, CINAHL, Scopus, Cochrane, and organizational websites.
View Article and Find Full Text PDFBackground: The Fundamentals of Care framework emphasizes a patient-centered approach that prioritizes the nurse-patient relationship and care environment to meet patients' basic needs, including oral hygiene. Recognized as crucial for preventing systemic health problems, oral care neglect is a global concern. Studies identify missed oral care as a widespread issue, contributing to significant patient safety risks.
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- Hereditary hemorrhagic telangiectasia (HHT) is a genetic disorder that leads to abnormal blood vessel formations, particularly in the skin and internal organs, due to mutations in one of three specific genes.
- Research indicates that these vascular malformations result from a two-hit mutation mechanism, where a primary genetic mutation is compounded by additional events such as somatic mutations or loss of heterozygosity.
- The study confirms that both skin and internal organ abnormalities share similar molecular processes, emphasizing that losing function in both copies of the HHT gene is essential for developing these vascular issues.
Cerebral Cavernous Malformations (CCMs) are vascular malformations of the central nervous system which can lead to moderate to severe neurological phenotypes in patients. A majority of CCM lesions are driven by a cancer-like three-hit mutational mechanism, including a somatic, activating mutation in the oncogene PIK3CA, as well as biallelic loss-of-function mutations in a CCM gene. However, standard sequencing approaches often fail to yield a full complement of pathogenic mutations in many CCMs.
View Article and Find Full Text PDFEvery time a patient undergoes a medical procedure, unpredicted personal stress occurs. According to the available literature, the hypnotic communication technique has been used to reduce stress and pain during several major invasive procedures. The primary goal of this study was to compare the effectiveness of hypnotic communication combined with buffered Lidocaine, versus buffered Lidocaine alone, on patients' negative emotions while undergoing Peripherally Inserted Central Venous Catheter (PICC) placement.
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