Publications by authors named "C J Favre"
Article Synopsis
- This study investigates how various factors affect the recovery paths of patients dealing with chronic pain and functional limitations after orthopedic injuries, emphasizing the role of rehabilitation in their journey to manage pain autonomously.
- Researchers conducted two in-depth interviews with 24 patients over a year, utilizing qualitative analysis to identify three distinct recovery trajectories: socio-professional reintegration, ongoing reintegration, and exclusion, influenced by both personal and social factors.
- The findings highlight the importance of understanding individual and societal influences on recovery, suggesting that this knowledge can help tailor rehabilitation efforts to enhance patients' reintegration into society and the workforce.
Hepatocellular carcinoma (HCC) associated with viral or metabolic liver diseases is a growing cancer without effective therapy. AMPK is downregulated in HCC and its activation diminishes tumor growth. Alpha lipoic acid (ALA), an indirect AMPK activator that inhibits hepatic steatosis, shows antitumor effects in different cancers.
View Article and Find Full Text PDFIschaemia-reperfusion (IR)-associated acute kidney injury (AKI) is a severe clinical condition that lacks effective pharmacological treatments. Our recent research revealed that pretreatment with the angiotensin II type 2 receptor (AT2R) agonist C21 alleviates kidney damage during IR. Primary cilia are organelles crucial for regulation of epithelial cell homeostasis, which are significantly affected by IR injury.
View Article and Find Full Text PDFPain has multiple consequences, forcing people to change the way they carry out their activities (domestic, work, leisure, social). Classically, three behavioural strategies have been described: avoidance, modulation, and persistence. Recent research suggests that the use of these strategies is more complex and subtle than previously imagined.
View Article and Find Full Text PDFIntroduction: To understand the family's role in adolescents' mental health development and the connection to neurodevelopmental disorders related to experienced parental physical abuse, we first explored resilience pathways longitudinally and secondly, connected the identified patterns to adolescents' hair cortisol levels that are rooted in the hypothalamic-pituitary-adrenal axis as the main stress response system and connected brain structure alterations.
Methods: We analyzed longitudinal online questionnaire data for three consecutive high school years (from seventh to ninth grade) and four survey waves from a representative sample of = 1609 high school students in Switzerland on violence-resilience pathways. Furthermore, we collected students' hair samples from a subsample of = 229 at survey wave 4.