Publications by authors named "C J Faust"

Article Synopsis
  • Anthropogenic land-use change is a significant factor in global biodiversity loss and poses health risks through biological interactions.
  • An analysis of a 43-year dataset on rodents in Central China shows that land consolidation led to larger habitat patches, a shift in rodent communities, and a drastic decline in diversity, with most species nearly disappearing.
  • The study emphasizes that land consolidation favored the striped field mouse, a key host for Hantaan virus, illustrating the need to consider the impacts of human activities on biodiversity and public health management.
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Objective: To study the impact of a CT serology on intrauterine insemination (IUI) cumulative live-birth rate (cLBR) in women with documented bilateral tubal patency.

Design: Cohort study SUBJECTS: Infertile women with documented bilateral tubal patency and medical indication of IUI matched on the following criteria: woman's age, number of cycles completed and number of motile sperm inseminated (NMSI).

Exposure: This retrospective, observational and monocentric cohort study compared women with positive CT serology matched 1:1 to control women with negative CT serology.

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While bioactivity and a favorable safety profile for biotherapeutics is of utmost importance, manufacturability is also worth of consideration to ease the manufacturing process. Manufacturability in the scientific literature is mostly related to stability of formulated drug substances, with limited focus on downstream process-related manufacturability, that is, how easily can a protein be purified. Process-related impurities or biological impurities like viruses and host cell proteins (HCP) are present in the harvest which have mostly acid isoelectric points and need to be removed to ensure patient safety.

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Article Synopsis
  • Many people worldwide want to find ways to stop future pandemics from happening.
  • While there has been a lot of focus on preparing for and responding to pandemics, preventing diseases from spreading from animals to humans isn't talked about much.
  • The text suggests we should pay more attention to how environmental changes can cause these spills and offers ideas on how to make policies that help prevent them.
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Vision relies on the continuous exchange of material between the photoreceptors, retinal pigment epithelium and choriocapillaris, a dense microvascular bed located underneath the outer retina. The anatomy and physiology of the choriocapillaris and their association with retinal homeostasis have proven difficult to characterize, mainly because of the unusual geometry of this vascular bed. By analysing tissue dissected from 81 human eyes, we show that the thickness of the choriocapillaris does not vary significantly over large portions of the macula or with age.

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