Publications by authors named "C J F Fontes"

Background:  Optic neuritis is an inflammation of the optic nerve caused by genetic factors, external influences, and the activation of cross-reactive immune responses to infections.

Objective:  To describe the clinical and epidemiological characteristics of patients presenting optic neuritis as the initial symptom of some demyelinating diseases, divided among multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG)-associated disorders (MOGADs).

Methods:  Thirty-eight patients who had optic neuritis as their first symptom and later developed MS, NMOSD, or MOGADs were analyzed.

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The self-consistent inclusion of plasma effects in opacity calculations is a significant modeling challenge. As density increases, such effects can no longer be treated perturbatively. Building on a a recently published model that addresses this challenge, we calculate opacities of oxygen at solar interior conditions.

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Article Synopsis
  • The diversity of β-glucans leads to their various biological functions, necessitating multiple enzymes for their assembly and breakdown, along with new discoveries for potential biotechnological uses.
  • Recent studies have identified and characterized two bacterial β-glucanases, LaGH157 and BcGH157, from the glycoside hydrolase family 157, detailing their structures and functions in hydrolysis.
  • Both enzymes display optimal activity at specific pH and temperature ranges and exhibit unique cleavage patterns, expanding knowledge on β-glucan processing and suggesting future applications in biotechnology.
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  • - The study examines the impact of platelet-rich plasma (PRP) on uterine inflammation and pregnancy rates in jennies (female donkeys) inseminated with frozen donkey semen, which generally shows lower success in jennies compared to mares.
  • - Three groups of jennies were tested: a control group with no treatment, a group receiving a single PRP infusion, and a group getting double PRP infusions around ovulation and artificial insemination (AI).
  • - Results indicated that while S-PRP reduced intrauterine fluid (IUF) accumulation shortly after AI, no significant differences were observed in pregnancy rates among groups, suggesting PRP treatments did not effectively improve outcomes for jennies
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Sophisticated tools such as computer vision techniques in combination with 1D lineout type analyses have been used in automating the analysis of spectral data for high energy density (HED) plasmas. Standardized automation can solve the problems posed by the complexity of HED spectra and the quantity of data. We present a spectroscopic code written for automated and streamlined analysis of spatially resolved x-ray absorption data from the COAX platform on Omega-60.

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