Publications by authors named "C J DUNNE"
Metaproteomic analysis of microbiome post-translation modifications (PTMm) is challenging, and little is known about the effects of inflammation on the bacterial PTM landscape in IBD. Here, we adapted and optimised fluorescence in situ hybridisation-flow cytometry (FISH-FC) to study microbiome-wide tyrosine phosphorylation (p-Tyr) in children with and without inflammatory bowel disease (IBD). Microbial p-Tyr signal was significantly higher in children with IBD, compared to those without.
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- The management of foreign body airway obstruction has shifted from older methods like back blows and chest thrusts to abdominal thrusts, but current guidelines are based on outdated and unclear data regarding their effectiveness and safety.
- Concerns exist about the potential for injury, especially in children, indicating a need for a thorough revision of first aid practices to ensure child safety in choking situations.
- Recent studies highlight inconsistencies in existing guidelines, largely rely on low-quality evidence, and emphasize the necessity to update training and recommendations based on more reliable, evidence-based research.
Background: Hospital wastewater systems have been identified as reservoirs for antibiotic-resistant bacteria, with biofilms harbouring extended-spectrum β-lactamase (ESBL)-producing micro-organisms posing significant infection risk.
Aim: To study the antimicrobial susceptibility and biofilm control of ESBL-producing bacteria from wastewater pipes from a tertiary care teaching hospital in Ireland, which had experienced endemic infection outbreaks caused by ESBL-producing bacteria.
Methods: Following isolation of ESBL producers on selective agar, antibiotic susceptibility profiles were determined for a number of antibiotics assessed for their ability to form biofilms.
With large wildfires becoming more frequent, we must rapidly learn how megafires impact biodiversity to prioritize mitigation and improve policy. A key challenge is to discover how interactions among fire-regime components, drought and land tenure shape wildfire impacts. The globally unprecedented 2019-2020 Australian megafires burnt more than 10 million hectares, prompting major investment in biodiversity monitoring.
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- * Resuscitation efforts for drowning victims must prioritize restoring breathing as well as circulation, with in-water rescue breathing followed by chest compressions once the victim is in a safe environment.
- * Recent updates to resuscitation guidelines for drowning, based on systematic reviews from 2021 to 2023, have been established by a committee of experts from the American Academy of Pediatrics and the American Heart Association.