Publications by authors named "C J Correia"
Nervous system disorders are characterized by a progressive loss of function and structure of neurons that ultimately leads to a decline in cognitive and motor functions. In this study, we used interfacial polyelectrolyte complexation (IPC) to produce fibers for neural tissue regeneration. IPC is a processing method that allows spinning of sensitive biopolymers.
View Article and Find Full Text PDFHemodialysis for chronic kidney disease (CKD) relies on vascular access (VA) devices, such as arteriovenous fistulas (AVF), grafts (AVG), or catheters, to maintain blood flow. Nonetheless, unpredictable progressive vascular stenosis due to neointimal formation or complete occlusion from acute thrombosis remains the primary cause of mature VA failure. Despite emergent surgical intervention efforts, the lack of a reliable early detection tool significantly reduces patient outcomes and survival rates.
View Article and Find Full Text PDFIn the 2018 yellow fever (YF) outbreak in Brazil, we generated new transcriptomic data and combined it with clinical and immunological data to decode the pathogenesis of YF. Analyzing 79 patients, we found distinct gene expression patterns between acute YF, other viral infections, and the milder YF-17D vaccine infection. We identified a critical role for low-density, immature neutrophils in severe outcomes, marked by the downregulation of genes essential for neutrophil migration and maturation, such as PADI4, CSF3R, and ICAM1, in deceased patients.
View Article and Find Full Text PDFArticle Synopsis
- * The hydrophobic nature of E2 makes it challenging to create effective delivery systems, but recent advancements in nano-based delivery systems, particularly lipid and polymeric nanoparticles, show promise in improving E2's stability and targeted delivery.
- * This review highlights the lack of extensive research on nano-delivery strategies for E2, emphasizing the need for more studies to develop and implement these therapies in clinical settings.
Objective: To analyze the spiritual well-being of nursing professionals with work-related musculoskeletal disorders.
Method: Cross-sectional observational study, carried out with nursing professionals from a public university hospital in Bahia, Brazil, from March to June 2023. Data was collected in a face-to-face interview in which sociodemographic, clinical and occupational data were extracted, in addition to the Spiritual Well-Being Scale application.