Publications by authors named "C Ileen Jhaney"
Exploring the Anal Microbiome in HIV Positive and High-Risk HIV Negative Women.
AIDS Res Hum Retroviruses
March 2022
This exploratory study sought to characterize the anal microbiome and explore associations among the anal microbiome, risk factors for anal cancer, and clinical factors. A pilot sample of 50 HIV infected and high-risk HIV negative women were recruited from the former Women's Interagency HIV Study. Microbiome characterization by 16S rRNA gene sequencing and datasets were analyzed using QIIME 2™.
View Article and Find Full Text PDFBackground: Evidence suggests that intravaginal practices (IVPs) women use to cleanse their vagina or enhance sexual pleasure may be associated with unhealthy changes in the vaginal microbiome (VM). However, the effects of these practices in postmenopausal women are unknown.
Objectives: The objective of this pilot study was to characterize the VM communities of postmenopausal women, identify types and frequency of IVPs, and explore associations between the VM and IVPs in postmenopausal women.
Article Synopsis
- - The study investigates racial disparities in diffuse large B-cell lymphoma (DLBCL) in the U.S., focusing on whether genetic ancestry influences tumor genomic alterations among patients.
- - The analysis of 1,001 DLBCL patients revealed significant differences, such as younger age and worse overall survival in those with African ancestry compared to those with European ancestry.
- - Additionally, certain driver genes were more frequently mutated in African ancestry patients, indicating unique mutational patterns and potential underlying biological mechanisms related to DLBCL.