Publications by authors named "C I Ripamonti"
Objective: To investigate the long-term effects of intravenous neridronate treatment in patients with complex regional pain syndrome type 1 (CRPS) in a real-life setting.
Methods: We conducted a retrospective study on consecutive CRPS patients treated at our hospital from February 2018 to July 2023. All were treated within three months of the onset of CRPS symptoms.
Article Synopsis
- The study explores gene therapy targeting L-cone opsin expression as a treatment for blue cone monochromacy (BCM), a condition caused by the lack of long- and middle-wavelength-sensitive cone function.
- Eight patients with BCM underwent various assessments, including optical coherence tomography and chromatic perimetry, revealing outer retinal changes and significant deficiencies in color vision and visual acuity.
- The research emphasizes the need for specialized outcome measures, such as dark-adapted microperimetry and specific visual acuity tests, to evaluate the efficacy and safety of potential future treatments in clinical trials.
Experimental and observational studies have shown that opioid analgesics may increase tumor growth, potentially reduce immunotherapy efficacy, and shorten survival. As a result of the lack of clinical data, the current rationale for continuing opioid analgesic treatment is based on animal models, which suggests that physical pain itself may potentially influence cancer growth and exert immunosuppressive effects. Total pain encompasses the various factors that patients may experience during their cancer journey: physical symptoms, social isolation/loneliness, psychological, spiritual/existential, and financial distress.
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