Publications by authors named "C Hubbard"

Patients who reside in areas of high neighborhood disadvantage have poorer health outcomes; the mechanisms for this disparity are complex. We sought to determine if there was an association between neighborhood disadvantage and diagnostic error among a cohort of adult inpatients who experienced either an ICU transfer or in-hospital death. Using a sample of 527 patients from seven geographically diverse academic medical systems, we compared diagnostic error rates to patients' neighborhood disadvantage levels as measured by the Area Deprivation Index, a validated composite measure of socioeconomic status.

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Targeting tumor-specific molecular alterations has shown significant clinical benefit. Molecular tumor boards (MTBs) connect cancer patients with personalized treatments and clinical trials. However, rural cancer centers often have limited access to MTB expertise.

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Article Synopsis
  • A maximal apnoea poses significant challenges to the body, impacting arterial blood gases and requiring complex responses from multiple physiological systems like blood pressure and cerebral blood flow.
  • Previous research has largely concentrated on cardiovascular responses during maximal apnoea, with limited exploration into respiratory muscle responses and respiratory mechanics.
  • This review suggests that respiratory muscles may fatigue after maximal apnoea and proposes that elite divers may possess greater fatigue resistance, which could contribute to their success; it also highlights the need for further studies on the long-term health effects of apnoea diving.
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Maximal static dry, that is, on land, apneas (breath-holds) result in severe hypoxemia and hypercapnia and have easy-going and struggle phases. During the struggle phase, the respiratory muscles involuntarily contract against the closed glottis in increasing frequency and magnitude, that is, involuntary breathing movements (IBMs). IBMs during maximal static apnea have been suggested to fatigue respiratory muscles, but this has yet to be measured.

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Background: Current hypertension treatments rely on chronological age, which may not reflect individual differences in aging and its impact on cardiovascular health. This study aimed to determine whether biological age can predict adverse outcomes in older adults with hypertension, independent of traditional risk factors including chronological age.

Methods: An analysis of a prospective cohort was conducted using data from the Health and Retirement Study, a longitudinal survey of older adults in the United States.

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