Publications by authors named "C Holliday"

Article Synopsis
  • In 2022, researchers observed gray bats with notable fur loss (alopecia), indicating potential health issues related to reproductive stages and other stress factors.
  • In 2023, an experiment was conducted to assess alopecia's prevalence, severity, and associated ectoparasites in gray bats, with findings revealing no mites causing fur loss and different prevalence rates between genders.
  • The study showed that lactating female bats tend to experience more severe alopecia compared to males, and no significant body condition difference was found between bats with and without fur loss, suggesting the need for further research on stress and nutritional support for these bats.
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CD8 T cell exhaustion hampers control of cancer and chronic infections and limits chimeric antigen receptor (CAR) T cell efficacy. Targeting in CAR T cells provides therapeutic benefit; however, TET2's role in exhausted T cell (T) development is unclear. In chronic lymphocytic choriomeningitis virus (LCMV) infection, TET2 drove conversion from stem cell-like T progenitors toward terminally differentiated and effector (T)-like T.

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In the standard approach to hip arthroscopy, access to the joint is achieved using fluoroscopic guidance to enter the central compartment of the hip using the Seldinger technique, penetrating the capsule with a needle and subsequently cannulating and obtaining direct visualization of the joint. In such a way, arthroscopists then proceed with accessory portal creation and capsulotomy, as desired, under direct intra-articular visualization. In cases with severe pincer morphology or coxa profunda, it may not be possible to safely access the central compartment under fluoroscopic guidance due to significant lateral overcoverage of the femoral head.

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Article Synopsis
  • Traditional treatment for unstable osteochondritis dissecans lesions in the medial femoral condyle involves open surgery with direct visualization.
  • This study introduces an arthroscopic method for treating these lesions which includes elevation, cleaning, and fixation without a large incision.
  • The new technique preserves surrounding soft tissues and enhances recovery by utilizing specialized instruments for a less invasive approach.
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Background: Therapeutic options for early-stage hepatocellular carcinoma (HCC) in individual patients can be limited by tumor and location, liver dysfunction and comorbidities. Many patients with early-stage HCC do not receive curative-intent therapies. Stereotactic ablative body radiotherapy (SABR) has emerged as an effective, non-invasive HCC treatment option, however, randomized evidence for SABR in the first line setting is lacking.

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