Publications by authors named "C Herve"
Article Synopsis
- Brown seaweeds are vital to coastal ecosystems, but they are threatened by climate change, prompting a detailed genetic study.
- The research traced the evolutionary history of brown algae, highlighting significant gene families and metabolic pathways related to their adaptation and functional diversity.
- Findings also indicated that the integration of large viral genomes has played a crucial role in shaping the genetics and traits of brown algal species over time.
Carrageenans are major gel forming polysaccharides in the extracellular matrix of the red macroalga Chondrus crispus. These galactans are made of linear chains of repetitive disaccharide motifs based on d-galactose residues alternately linked by β-1,4 and α-1,3 glycosidic bonds. A definite number of disaccharide motifs are known, based on their regular sulfations and the presence of a 3,6-anhydro bridge.
View Article and Find Full Text PDFBackground: Brown algae belong to the Stramenopiles phylum and are phylogenetically distant from plants and other multicellular organisms. This independent evolutionary history has shaped brown algae with numerous metabolic characteristics specific to this group, including the synthesis of peculiar polysaccharides contained in their extracellular matrix (ECM). Alginates and fucose-containing sulphated polysaccharides (FCSPs), the latter including fucans, are the main components of ECMs.
View Article and Find Full Text PDFArticle Synopsis
- - The study explored the effectiveness of combining curcumin with docetaxel for patients with advanced and metastatic breast cancer, focusing on whether this combination improved treatment response rates.
- - Conducted across multiple centers, the research included 42 patients and aimed to compare the objective response rates and other clinical outcomes between the two treatment groups but found no significant differences.
- - Ultimately, the study concluded that adding curcumin to docetaxel did not enhance efficacy and was deemed safe, leading to the decision to stop the trial due to lack of meaningful results, while suggesting further research with adjustments for more conclusive findings.