Publications by authors named "C Herrera Ligero"
Background: Amiodarone is an anti-arrhythmic drug that has extensive tissue distribution and substantial storage in the fat tissue. Different studies have described some implications of body fat composition in its pharmacokinetics and pharmacodynamics. However, no clinical studies have described its implications for clinical efficacy.
View Article and Find Full Text PDFIntroduction And Purpose: Bicuspid aortic valve (BAV) disease is associated with faster aortic valve degeneration and a high incidence of aortic stenosis (AS). In this study, we aimed to identify differences in the pathophysiology of AS between BAV and tricuspid aortic valve (TAV) patients in a multiomics study integrating metabolomics and transcriptomics as well as clinical data.
Methods: Eighteen patients underwent aortic valve replacement due to severe aortic stenosis: 8 of them had a TAV, while 10 of them had a BAV.
Importance: Despite the importance of pronosupination strength, which is key in daily activities, current evaluation protocols are disparate, and results differ regarding the influence of factors such as gender, age, limb dominance, or posture.
Objective: To design a reliable device to measure pronation and supination torques in different forearm positions, considering the influence of gender, age, and limb dominance.
Design: Reliability study with analysis of intrarater and interrater repeatability and examination of the influence of different factors on the strength of pronation and supination.
Article Synopsis
- A study investigates the relationship between Body Mass Index (BMI) and the recurrence of atrial fibrillation (AF) after patients undergo electrical cardioversion (ECV), with a focus on individuals classified as normal weight, overweight, and obese.
- Out of 1121 patients analyzed, 48% experienced AF recurrence within three months, with a notable correlation between higher BMI and increased recurrence rates, particularly among those who are overweight and obese.
- The findings suggest that a BMI of 25 kg/m² or higher is linked to a greater likelihood of AF recurrence post-ECV, underscoring the need to consider a patient's BMI in ECV decision-making for persistent AF.
Introduction: The bicuspid aortic valve (BAV) confers a high risk of ascending aorta dilatation (AAoD), although its progression seems highly variable. Furthermore, the implication of lipoprotein metabolism and inflammation in the mechanisms that underlie AAoD is not fully established. The aim of this study consisted of evaluating the impact of the lipoprotein and glycoprotein profiles in AAOD as well as its progression in BAV aortopathy.
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