Cellular sex throughout the organism underlies somatic sexual differentiation.

Sex chromosomes underlie the development of male or female sex organs across species. While systemic signals derived from sex organs prominently contribute to sex-linked differences, it is unclear whether the intrinsic presence of sex chromosomes in somatic tissues has a specific function. Here, we use genetic tools to show that cellular sex is crucial for sexual differentiation throughout the body in Drosophila melanogaster.

Striking the Balance: Embracing Technology While Upholding Humanistic Principles in Neurorehabilitation.

Background: The rapid advancement of technology-focused strategies in neurorehabilitation has brought optimism to individuals with neurological disorders, caregivers, and physicians while reshaping medical practice and training.

Objectives: We critically examine the implications of technology in neurorehabilitation, drawing on discussions from the 2021 and 2024 World Congress for NeuroRehabilitation. While acknowledging the value of technology, it highlights inherent limitations and ethical concerns, particularly regarding the potential overshadowing of humanistic approaches.

Creative connections: the neural correlates of semantic relatedness are associated with creativity.

The associative theory of creativity proposes that creative ideas result from connecting remotely related concepts in memory. Previous research found that higher creative individuals exhibit a more flexible organization of semantic memory, generate more uncommon word associations, and judge remote concepts as more related. In this study (N = 93), we used fMRI to investigate brain regions involved in judging the relatedness of concepts that vary in their semantic distance, and how such neural involvement relates to individual differences in creativity.