Publications by authors named "C HeiSS"
Background: Accumulation of malignant plasma cells in the bone marrow causes lytic bone lesions in 80% of multiple myeloma patients. Frequently fracturing, they are challenging to treat surgically. Myeloma cells surviving treatment in the presumably protective environment of bone lesions impede their healing by continued impact on bone turnover and can explain regular progression of patients without detectable minimal residual disease (MRD).
View Article and Find Full Text PDFUnlabelled: is considered one of the most challenging, drug-resistant, opportunistic pathogens partly due to its ability to synthesize robust biofilms. Biofilm is a mixture of extracellular polymeric substances (EPS) that encapsulates microbial cells, leading to immune evasion, antibiotic resistance, and thus higher risk of infection. In the cystic fibrosis lung environment, undergoes a mucoid transition, defined by overproduction of the exopolysaccharide alginate.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated three-year outcomes of endovascular treatment (EVT) for peripheral arterial disease (PAD) in patients with severe calcified lesions in the common femoral artery (CFA), using data from the Duesseldorf PTA Registry.
- A total of 150 patients were analyzed, with 66 undergoing rotational excisional atherectomy (REA) followed by drug-coated balloon (DCB) angioplasty, and 84 receiving DCB alone; the procedural success rate was high at 97%.
- Findings indicated that EVT is safe and effective, showing high primary and secondary patency rates, low major adverse limb events (MALEs), and major adverse cardiovascular events (MACEs) after three years, suggesting that RE
Background: Timely and economic provision of revascularisation procedures is a major healthcare need. We aimed to examine the safety and efficacy of daycase-based lower extremity endovascular revascularisation procedures in patients with peripheral artery disease.
Methods: In this systematic review and meta-analysis, we searched MEDLINE and Embase for studies from Jan 01, 2000 through Apr 01, 2024 reporting complications of lower limb endovascular revascularisation procedures with same-day discharge.