Multiscale morphological trajectories to support management of free-flowing rivers: the Vjosa in South-East Europe.

Free-flowing rivers (FFRs) are fundamental references for river management, providing the opportunity to investigate river functioning under minimal anthropic disturbance. However, large free-flowing rivers are rare in Europe and worldwide, and knowledge of their dynamics is often scarce due to a lack of data and baseline studies. So far, their characterization is mainly grounded in the longitudinal connectivity assessment, with scarce integration of further hydro-morphological aspects, particularly concerning the processes and drivers of changes in their morphology over time scales of management relevance.

Hydrogel-embedded precision-cut lung slices support culture of -induced premalignant lung lesions.

Lung cancer is the leading cause of global cancer death and prevention strategies are key to reducing mortality. Medical prevention may have a larger impact than treatment on mortality by targeting high-risk populations and reducing their lung cancer risk. Premalignant lesions (PMLs) that can be intercepted by prevention agents are difficult to study in humans but easily accessible in murine preclinical carcinogenesis studies.

Hydrogel-Embedded Precision-Cut Lung Slices Model Lung Cancer Premalignancy Ex Vivo.

Lung cancer is the leading global cause of cancer-related deaths. Although smoking cessation is the best prevention, 50% of lung cancer diagnoses occur in people who have quit smoking. Research into treatment options for high-risk patients is constrained to rodent models, which are time-consuming, expensive, and require large cohorts.

[Movement of a fluvial particle under the influence of coherent structures].

In a fundamental study the influence of coherent structures on the incipient motion of single fluvial grain was experimentally investigated. To fully characterize coherent structures, the three-dimensional velocity field must be known with high temporal resolution. Using a tr-3D PTV system (tr = time-resolved, PTV = particle tracking velocimetry) this could be achieved.