Publications by authors named "C Harms"

Article Synopsis
  • The use of "Wildling mice" with a natural microbiome presents a unique research tool for studying human-like immune systems, but poses challenges for animal husbandry due to their diverse microbial content.
  • A specialized facility was created at Charité - Universitätsmedizin Berlin to manage these mice, incorporating unique designs and protocols for hygiene and microbiome containment.
  • The study shows that "Wildling mice" develop distinct immune cell populations compared to SPF mice, suggesting that using these mice could improve the relevancy of preclinical findings for human health.
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Leatherback turtles () are endangered by anthropogenic threats. Characterizing the physiologic response of leatherback turtles under various stressors may inform conservation strategies. In this study, a commercially available enzyme immunoassay for aldosterone was validated for leatherback turtle plasma, and it was used with previously validated assays for corticosterone and free thyroxine (fT4) to evaluate the physiologic status of leatherback turtles that were entangled in fishing gear, stranded on shore, nesting or intentionally captured at sea during ecologic studies.

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Objective: The objective of this study was to use body surface area (BSA) obtained via computed tomography (CT) to calculate a species-specific shape constant (K) and provide a formula for BSA based on body weight (BW) in Atlantic Stingrays Hypanus sabina. Ultimately, this information can be used to more accurately calculate chemotherapeutic doses and other metabolic-related measures.

Methods: Six deceased Atlantic Stingrays of unknown age and with a range of sizes were collected during a natural mortality event and underwent CT scans.

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Predicting and mitigating the impacts of anthropogenic ocean noise on marine animals is hindered by a lack of information on hearing in these species. We established a catch-and-release program to temporarily hold adolescent minke whales () for hearing tests during their summer migration. In 2023, two minke whales provided measures of the auditory brainstem response and data on the frequency range of their hearing.

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Earth-abundant transition metal oxides are promising alternatives to precious metal oxides as electrocatalysts for the oxygen evolution reaction (OER) and are intensively investigated for alkaline water electrolysis. OER electrocatalysis, like most other catalytic reactions, is surface-initiated, and the catalyst performance is fundamentally determined by the surface properties. Most transition metal oxide catalysts show OER activities that depend on the predominantly exposed crystal facets/surface structure.

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